{"product_id":"bonusan-same-400-complex-2x30-capsulas","title":"Bonusan Same-400 Complex , 2X30 Capsules","description":"\u003cp\u003eS-Adenosyl Methionine (SAMe) is a sulphur-containing amino acid produced mainly in the liver and not found in food. It can be formed in the body by a combination of adenosine triphosphate (ATP) and the amino acid L-methionine. SAMe plays a role in the transfer of sulphur in the body and is converted, via the methionine cycle, into cysteine, which can be converted back into glutathione or taurine. SAMe also plays a role in the formation of creatine, which is important for athletes. Melatonin needs SAMe as a methyl donor. As we age, our own ability to create SAMe decreases.\u003cbr\u003eWe cannot get SAMe from our diet. The amino acid methionine can be found in the diet, but it is a less efficient way of supplementing SAMe. Sometimes SAMe production is deficient and declines with increasing age. Supplementing this body substance by means of a dietary supplement may then provide a solution.\u003cbr\u003e\u003cbr\u003eThe benefits of SAMe-400 complex from Bonusan\u003cbr\u003e\u003cbr\u003eBonusan SAMe-400 capsules are easy to dose. One capsule contains 400 mg of SAMe-disulphate tosylate which provides 200 mg of SAMe, natural S-Adenosyl methionine. In scientific studies, a multiple of 200 mg SAMe is always used. We recommend starting with a dose of one to three capsules per day (200 to 600 mg of active SAMe). It is best to increase the daily dose of SAMe slowly. In some cases, it helps to take a higher dose (800 to 1200 mg per day) over several weeks. In therapeutic treatments, a dose of 800-1600 mg per day works effectively. When SAMe is taken orally, it is best taken on an empty stomach or half an hour before meals.\u003cbr\u003eBecause SAMe is the body's own substance, it is well absorbed. Benefits are quickly experienced after starting SAMe supplementation. SAMe-400 complex from Bonusan is often popular and well tolerated because the natural raw material has few or no side effects.\u003cbr\u003e\u003cbr\u003eHigh quality thanks to stabilised SAMe\u003cbr\u003e\u003cbr\u003eThe SAMe containing SAMe-400 from Bonusan is produced from fermentation. In fermentation, only S,S SAMe (spatial form) is produced. We use this spatial form in our products because this is the form in which it occurs naturally in the body, so we stay close to the natural form. The synthetic form R,S has a different spatial configuration, which means it cannot be used by the body. Therefore, we do not incorporate this synthetic form in our supplement.\u003cbr\u003eThe SAMe used in Bonusan SAMe-400 is stabilised. The bond with tosylate disulphate makes our raw material the most stable form of SAMe. Unstabilised and unprotected SAMe is very sensitive to heat and moisture and will lose its effect quickly. Because of this high sensitivity to moisture, the manufacture of high quality SAMe requires a meticulous production process. The entire process in our factory is designed accordingly, from raw material to finished product. To guarantee the high quality of Bonusan SAMe-400 also outside our factory, we pack the capsules hermetically in a blister pack. Furthermore, we recommend that the product is not stored in damp areas, such as the kitchen or bathroom. In this way, you maintain the best possible quality until the end of the product's shelf life.\u003cbr\u003e\u003cbr\u003eSuitable for supplementing the body's own SAMe\u003cbr\u003e\u003cbr\u003eOne capsule of Bonusan SAMe-400 contains 400 mg SAMe-disulphate tosylate which provides 200 mg of SAMe, natural S-Adenosyl methionine. When the body's own production is insufficient or declines as we age, this carefully produced SAMe-400 complex offers a solution. SAMe can be useful in many different doses. Determining the correct dosage is often part of a therapeutic treatment. In cases where a high dose is necessary, gradually increasing the daily dose may help prevent nausea and gastrointestinal discomfort. We recommend that you consult a specialist when using SAMe. SAMe-400 complex from Bonusan contains no substances of animal origin and is therefore suitable for vegetarians and vegans.\u003c\/p\u003e\n\u003ch2\u003eComposition\u003c\/h2\u003e\n\u003cp\u003eComposition per capsule Contains:\u003cbr\u003eS-Adenosyl-L-Methionine natural (from SAMe-disulphate tosylate) 200.00 mg\u003c\/p\u003e\n\u003ch2\u003eInstructions for use\u003c\/h2\u003e\n\u003cp\u003eUnless otherwise advised, take 1-3 capsule(s) at least half an hour before a meal.\u003cbr\u003ebefore a meal. Do not exceed the recommended daily dose.\u003c\/p\u003e\n\u003ch2\u003eIngredients\u003c\/h2\u003e\n\u003cp\u003eIngredients\u003cbr\u003eAdenosyl methionine, capsule shell (hydroxypropyl methylcellulose), bulking agent (microcrystalline cellulose), anti-crystalline\u003cbr\u003e(microcrystalline cellulose), anti-caking agent (rice fibres).\u003cbr\u003eSAMe-400 complex\u003cbr\u003eDoes not contain\u003cbr\u003eCorn, yeast, added sucrose, preservatives, artificial colours, flavours and flavourings.\u003c\/p\u003e\n\u003ch2\u003ePharmaceutical advice\u003c\/h2\u003e\n\u003cp\u003eNot recommended for people with bipolar disorder. Consult a doctor before use if you are pregnant or breastfeeding.\u003c\/p\u003e","brand":"BONUSAN","offers":[{"title":"Default title","offer_id":55606085321087,"sku":"BO3520260818161","price":90.1,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0638\/8829\/4065\/files\/bonusan-same-400-complex-2x30-capsulas-227011_0d550b85-a8e2-466f-afa4-3389bce7a34d.webp?v=1784380065","url":"https:\/\/farmaciasdirect-eu.myshopify.com\/products\/bonusan-same-400-complex-2x30-capsulas","provider":"Farmaciasdirect.eu","version":"1.0","type":"link"}