{"product_id":"strefen-honey-eucalyptus-16-lozenges","title":"Strefen Honey Eucalyptus, 16 lozenges","description":"\u003ch2\u003eWhat is Strefen Honey Eucalyptus 16 lozenges and what is it for?\u003c\/h2\u003e\n\u003cp\u003eStrefen Honey Eucalyptus provides short-term symptomatic relief of \u003cstrong\u003esore throat pain\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch2\u003eWho is it intended for?\u003c\/h2\u003e\n\u003cp\u003eIt is intended for adults and adolescents over 12 years of age.\u003c\/p\u003e\n\u003ch2\u003eHow to use: Dosage\u003c\/h2\u003e\n\u003cp\u003eThe lowest dose that is effective for the shortest possible time should be administered to control symptoms.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdults and adolescents aged 12 years and over:\u003c\/strong\u003e Dissolve or suck one lozenge slowly in the mouth every 3-6 hours as needed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaximum:\u003c\/strong\u003e 5 lozenges in a 24-hour period.\u003c\/li\u003e\n\u003cli\u003eIt is recommended to use this medicine for a maximum of 3 days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChildren:\u003c\/strong\u003e Not indicated for children under 12 years of age.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElderly patients:\u003c\/strong\u003e General dosage cannot be recommended due to limited clinical experience. These patients are at increased risk of serious adverse effects.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHepatic insufficiency:\u003c\/strong\u003e No dose reduction is required in patients with mild to moderate hepatic insufficiency. Flurbiprofen is contraindicated in patients with severe hepatic impairment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRenal insufficiency:\u003c\/strong\u003e No dose reduction is required in patients with mild to moderate renal insufficiency. Flurbiprofen is contraindicated in patients with severe renal insufficiency.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eRoute of administration: How to take\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eBy mouth\u003c\/strong\u003e, for short-term use only.\u003c\/p\u003e\n\u003cp\u003eAs with all\u003cstrong\u003e lozenges\u003c\/strong\u003e, to avoid local irritation, Strefen should be kept in motion in the mouth while dissolving.\u003c\/p\u003e\n\u003ch2\u003eContraindications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eContraindicated in children under 12 years of age.\u003c\/li\u003e\n\u003cli\u003eKnown hypersensitivity to flurbiprofen or allergy to non-steroidal anti-inflammatory drugs (NSAIDs).\u003c\/li\u003e\n\u003cli\u003ePatients with a history of hypersensitivity to acetylsalicylic acid or other NSAIDs, including those who have experienced asthma attacks, acute rhinitis, urticaria or angioneurotic oedema following the use of acetylsalicylic acid or other NSAIDs.\u003c\/li\u003e\n\u003cli\u003eGastrointestinal bleeding, active peptic ulcer.\u003c\/li\u003e\n\u003cli\u003eSevere renal insufficiency (ClCr \u0026lt; 30 ml\/min).\u003c\/li\u003e\n\u003cli\u003eSevere hepatic insufficiency (Child-Pugh class C).\u003c\/li\u003e\n\u003cli\u003eSevere heart failure.\u003c\/li\u003e\n\u003cli\u003eThird trimester of pregnancy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003ePregnancy\u003c\/h2\u003e\n\u003cp\u003eInhibition of prostaglandin synthesis may adversely affect gestation and\/or embryo development. Epidemiological study data indicate an increased risk of miscarriage, cardiac malformations and gastroschisis after taking prostaglandin synthesis inhibitors in early pregnancy. The absolute risk of cardiovascular malformations increased from less than 1% to approximately 1.5%. The risk appears to increase as a function of dose and duration of treatment.\u003c\/p\u003e\n\u003cp\u003eAnimal studies have shown that administration of prostaglandin synthesis inhibitors results in increased pre- and post-implantation fetal loss and embryofetal lethality. Additionally, an increased incidence of several malformations, including cardiovascular malformations, has been reported in animals administered a prostaglandin synthesis inhibitor during the period of organogenesis. During the first and second trimester of pregnancy, flurbiprofen should be avoided unless strictly necessary. If flurbiprofen is administered to a woman planning to conceive, or during the first and second trimester of pregnancy, the lowest dose that is effective for the shortest possible time should be administered.\u003c\/p\u003e\n\u003cp\u003eDuring the third trimester of pregnancy, all prostaglandin synthesis inhibitors may expose the fetus to the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRenal and urinary:\u003c\/strong\u003e interstitial nephritis, nephrotic syndrome and renal failure.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003ePrecautions\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRenal insufficiency:\u003c\/strong\u003e Use contraindicated in severe renal insufficiency. NSAIDs may cause a decrease in renal blood flow, resulting in reversible acute renal failure due to inhibition of vasodilator prostaglandin synthesis. Nephrotic syndrome and acute interstitial nephritis have been reported with prolonged treatment. Patients at increased risk of renal failure are those with previous renal failure, the elderly, or those with conditions that may reduce renal flow, such as hypovolaemia, dehydration, low sodium diets, heart failure, liver failure, kidney failure.aca, liver failure, liver cirrhosis or treatment with diuretics, angiotensin-converting enzyme inhibitors (ACE inhibitors) or angiotensin II receptor antagonists (ARBs). In high-risk patients, during prolonged treatment, it is recommended to monitor renal function (serum creatinine, CrCl) before starting treatment and periodically. In case of worsening renal function, a dose reduction may be necessary.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHepatic insufficiency:\u003c\/strong\u003e Use in severe hepatic insufficiency is contraindicated.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal toxicity:\u003c\/strong\u003e Treatment with NSAIDs has resulted in gastroduodenal ulcers, as well as bleeding and perforations that can be fatal. There is an increased risk of ulcers with high-dose or long-term treatment, in patients with a history of peptic ulcer, especially if they have already had gastrointestinal bleeding or perforation from NSAIDs, as well as in people with smoking, chronic alcoholism, or in elderly or debilitated patients. However, short-term treatment also carries risks.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eComposition\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eFlurbiprofen (buccal) 8.75 milligrams\u003c\/li\u003e\n\u003cli\u003eBenzyl alcohol (excipient) 0.00169 milligrams\u003c\/li\u003e\n\u003cli\u003eIsomalt (E-953) (excipient) 2.034 mg\u003c\/li\u003e\n\u003cli\u003eMaltitol (E-965) (excipient) 508,50 milligrams\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003ePharmaceutical advice\u003c\/h2\u003e\n\u003cp\u003eAs a general rule, to reduce gastric damage, it is advisable to administer any NSAID with food. In addition, in at-risk groups it is recommended to start treatment with the lowest possible dose and, whenever feasible, to add an anti-ulcer drug (anti-H2 or proton pump inhibitor - PPI).\u003c\/p\u003e\n\u003ch2\u003eWhat is the price of Strefen Honey Eucalyptus, 16 tablets?\u003c\/h2\u003e\n\u003cp\u003eThe price of non-prescription medicines is set by law. However, at Farmaciasdirect you can buy Strefen Honey Eucalyptus, 16 tablets, with a discount of up to 10%, which is the legal maximum allowed.\u003c\/p\u003e","brand":"STREFEN","offers":[{"title":"Default title","offer_id":44536757584049,"sku":"ST8470007340522","price":12.56,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0638\/8829\/4065\/files\/strefen-miel-eucalipto-16-pastillas-16-pastillas_d81a66c0-3315-41c0-aaa5-44006a84892a.webp?v=1784375743","url":"https:\/\/farmaciasdirect-eu.myshopify.com\/products\/strefen-honey-eucalyptus-16-lozenges","provider":"Farmaciasdirect.eu","version":"1.0","type":"link"}